Manchester United were drawn against Real Betis in the Europa League round of 16 on Friday, while Arsenal will take on Sporting CP.
United edged to a 2-1 victory over Barcelona on Thursday to win the knockout round play-off tie 4-3 on aggregate.
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Arsenal did not play in the previous round due to finishing top of Group A.
The first legs of the last-16 ties will be played on March 9 and the second legs on March 16.
Europa League round of 16 draw
Union Berlin vs. Union Saint-Gilloise
Sevilla vs. Fenerbahce
Juventus vs. SC Freiburg
Bayer Leverkusen vs. Ferencvaros
Sporting CP vs. Arsenal
Manchester United vs. Real Betis
AS Roma vs. Real Sociedad